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Bioinformatics Analyst III

Company: Frederick National Laboratory for Cancer Research
Location: Gaithersburg
Posted on: August 17, 2019

Job Description:

The Cancer Genomics Research (CGR) laboratory in Gaithersburg, MD, is a fast-paced, high-throughput organization dedicated to the support of molecular, genetic and epidemiologic studies for investigators at the National Cancer Institute's Division of Cancer Epidemiology & Genetics (DCEG). The Division includes over 70 principal investigators in epidemiology, genetics, and biostatistics who conduct multidisciplinary family- and population-based research to discover the genetic and environmental determinants of cancer, and new approaches to cancer prevention. This includes the design and analysis of high throughput studies using various types of "-omics" technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis and molecular epidemiologic studies based on novel metabolomic and macrobiotic assays. We are seeking a highly motivated bioinformatics analyst to join the bioinformatics team at the CGR and provide analytical support to DCEG. Working with DCEG investigators, external collaborators, CGR management and staff, the successful incumbent will provide leadership and support to the extensive DCEG analytical efforts, specifically:KEY ROLES/RESPONSIBILITIES

  • Building, managing, and maintaining pipelines to facilitate high-throughput genomic data analysis
  • Performing large-scale data analysis and other support using third party software and our in-house pipelines, including (but not limited to) data QC, reference mapping, variant calling, annotation, microbiome and gene function analysis.
  • Contributing to the solutions of -omics analysis pipelines through exploring novel software, benchmarking, comparisons, testing, and troubleshooting
  • Implementing relational database models and web portals for scientific data.
  • Organizing results into clear presentations and concise summaries of work, in formats useful for scientific interpretation BASIC QUALIFICATIONS
    • Possession of a Bachelor's degree (Master's preferred) from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) in bioinformatics, computer science, computational biology or related field. Foreign degrees must be evaluated for U.S. equivalency
    • In addition to educational requirements, a minimum of five (5) years of related analytical or bioinformatics software development experience
    • Hands-on experience in processing sequencing, genotyping, expression and other data utilizing bioinformatics tools
    • The ability to construct practical computational tools for data parsing, quality control, modelling and analysis for large-scale genetic or genomics datasets
    • Demonstrable shell scripting skills (e.g. bash, awk, sed)
    • Strong programming skills (e.g., in one or more of Perl, Python, C/C++, Java)
    • Experience with design and use of relational SQL databases PREFERRED QUALIFICATIONS
      • Familiarity with public genomic tools, databases and utilities
      • Experience managing large datasets and computational tasks, experience working in a Linux environment (especially a computational cluster environment)
      • Experience in the field of molecular and population genetics with a strong publication record
      • Expertise in statistical programming and data manipulation (e.g. R, MATLAB) is desired
      • Team oriented with demonstrated ability to mentor others as well as self-educate in current bioinformatics techniques and resources
      • Excellent written and oral communication-ability to communicate clearly and effectively with staff and other groups within CGR and DCEG, and able to interpret data and write scientific reports as well as other written communications---Equal Opportunity Employer (EOE) - Minority/Female/Disabled/Veteran (M/F/D/V) - Drug Free Workplace (DFW)

Keywords: Frederick National Laboratory for Cancer Research, Washington DC , Bioinformatics Analyst III, Professions , Gaithersburg, DC

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