Scientist II, Research

Company: Horizon Therapeutics
Location: Gaithersburg
Posted on: March 19, 2023

Job Description:

Job Description:

At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved. Our global biotechnology company is made up of agile, out-of-the-box thinkers with a focus on delivering breakthrough medicines to those living with rare, autoimmune, and severe inflammatory diseases. This is the heart of our global mission. Start a career that enables you to live up to your potential and help others live up to theirs. Join us. The exceptional support we provide patients and communities equally extends to our employees. We offer industry-leading and award-winning benefits, compensation and rewards programs that positively impact all areas of our employees' personal and professional lives. Position Summary: Horizon is currently seeking a cell-based assay specialist to support pre-clinical program development in autoimmunity and inflammation. This person will be responsible for overseeing the design and generation of cell lines to facilitate biomolecule screening. This person will also be responsible for the development and implementation of cell-based and cell reporter gene-based assays.Position RequirementsLead development of cell-based tools for screening biomoleculesGenerate stable reporter gene cell lines to support multiple early-stage pre-clinical programs, target validation work, and downstream applicationsDesign, develop and execute cell-based screening assaysCo-lead pre-clinical large molecule programsGenerate and analyze experimental data; troubleshoot efficiently, prepare written reports and impactful presentationsWork collaboratively as part of a multifaceted team of protein engineers and disease area experts and collaborate with other functions such as downstream bioassay teams and translational teamsTrain other scientists in the lab and clearly communicate scientific conceptsContribute to evaluation of business development opportunitiesPresent scientific data in internal and external meetingsQualifications and Skills Required:Ph.D in Biotechnology/Molecular Biology/Cell Biology or related field with 3+ years of postdoctoral and/or industry experience or master's degree in Biotechnology/Molecular Biology/Cell Biology or other related discipline with 8+ years of industry/biomedical experience.Deep understanding of cell line manipulation techniques (Lentivirus, CRISPR, etc.)Experience designing reporter gene constructs and cell lines is requiredA strong knowledge base of immunology, antibodies and/or biotherapeutics is desirableExperience in multi-color flow cytometry, tissue culture techniques, molecular techniques, MSD/ELISA, cytotoxicity assays is desirablePerform lab work independentlyExcellent organizational and record keeping skillsOutstanding communication and presentation skillsStrong publication recordOur ValuesTransparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful difference.Accountability: We do what's right for our patient communities through quality decisions and owning our successes and failures.Growth: We fiercely innovate and evolve to better ourselves, our communities and our patients.These three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleAt Horizon, we know that disease does not discriminate. We embrace the bold ideas of one another, foster a sense of belonging, and value inclusion. We attract and develop diverse talent because we believe that when people from different backgrounds and life experiences come together, we make lives better. Horizon intends that all qualified applications are given equal opportunity, and that selection decisions be based on job-related factors. We do not discriminate based on race, color, religion, gender, sexual orientation, national origin, age, disability, veteran status, or any other characteristics protected by law.

Keywords: Horizon Therapeutics, Washington DC , Scientist II, Research, Other , Gaithersburg, DC