In vivo Scientist/Sr Scientist, Oncology Research
Posted on: October 19, 2020
In vivo Scientist/Senior Scientist, Oncology Research
What is Happening at AstraZeneca
At AstraZeneca, we turn ideas into life changing medicines. Working
here means being ambitious, thinking big and working together to
make the impossible a reality. Were passionate about the potential
of science to address the unmet needs of patients around the world.
We commit to those areas where we believe we can really change the
course of medicine and bring big new insights to life.
AstraZenecas vision in Oncology is to push the boundaries of
science to change the practice of medicine, transform the lives of
patients living with cancer, and to ultimately eliminate cancer as
a cause of death. A broad pipeline of next-generation medicines is
A broad pipeline of next-generation medicines is focused
principally on four disease areas - breast, ovarian, lung and
We are seeking a highly motivated and independent Scientist/Senior
Scientist in cancer pharmacology with a track record of scientific
excellence in the area of in vivo cancer modelling, to join our
team in Gaithersburg, MD USA. As a Scientist/Senior Scientist you
will be a key member of a team focussed on delivering all aspects
of in vivo pharmacology support. You will bring your theoretical
and practical expertise to establish assay systems and deliver
datasets that will have direct impact on the drug discovery process
Our Gaithersburg, Maryland facility develops life-changing
medicines for people around the world. The modern, vibrant
scientific campus employs more than 3000 experts in our field, and
it is only a short drive from Washington, DC. It is filled with
cutting edge technology. Our work areas were built to facilitate
teamwork, safe interactions and cross functional science. We
believe employees who feel safe and are challenged by the work, are
positioned to be creatively inspired to deliver.
Main Activities and Responsibilities
- Working in this laboratory-based position within Oncology
Research you will develop, design, conduct and analyze both in vivo
and in vitro experiments to assess the function of our candidate
oncology drugs and dissect the mechanism of action of novel cancer
- You will be expected to support cross-functional teams and work
collaboratively with project leaders to ensure the timely
generation, and dissemination of critical program data, and
contribute to scientific publication goals.
- As a highly organized, self-motivated individual with a strong
background in laboratory science you will stay up to date with
relevant technical and intellectual scientific expertise in tumor
biology, pharmacology and cancer modelling and have a genuine
passion for this field of research.
- Scientist - BS in Biology, Pharmacology or other related
scientific discipline with 3-6 yrs. relevant scientific
- Senior Scientist MS in Biology, Pharmacology or other related
scientific discipline with more than 5 years experience in
- Scientist - MS in Biology, Pharmacology or other related
scientific discipline with 2-5 yrs. relevant scientific
- Senior Scientist PhD in Cancer Biology, Pharmacology
Necessary Skills and Experience Required
- Experience developing and working with complex in vivo models,
such as xenograft, patient derived xenograft (PDX), syngeneic and
autochthonous mouse models.
- Experience delivering in vivo pharmacology studies in mouse
tumor models, including dose-finding tolerability studies, PK/PD
and efficacy studies.
- Experience with a range of in vitro skills, e.g. cell culture,
molecular biology, immunoblotting, flow cytometry and ELISA.
- Works independently, assesses and reports data in a clear and
concise manner, with a clear understanding of its implications
within the overall context of drug discovery.
- Maintains a well-developed understanding of approaches to drug
discovery and applies a broader functional knowledge of the
procedures used by diverse project groups to support the department
- Strong interpersonal and collaboration skills together with
evidence of delivery in a team-oriented, collaborative
- Excellent communication and presentation skills
- A proven track record of high productivity and scientific
publications in peer reviewed journals.
Desirable for the role
- Biotechnology or pharmaceutical industry experience preferred
but not required.
At AstraZeneca when we see an opportunity for change, we seize it
and make it happen, because any opportunity no matter how small,
can be the start of something big. Delivering life-changing
medicines is about being entrepreneurial - finding those moments
and recognizing their potential. Join us on our journey of building
a new kind of organization to reset expectations of what a
bio-pharmaceutical company can be. This means were opening new ways
to work, groundbreaking cutting edge methods and bringing
unexpected teams together. Interested? Come and join our
So, whats next?
Are you already envisioning yourself joining our team? Good,
because we cant wait to hear from you.
Where can I find out more?
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Keywords: AstraZeneca, Washington DC , In vivo Scientist/Sr Scientist, Oncology Research, Healthcare , Gaithersburg, DC
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